Genes, genomes, and cancer
نویسندگان
چکیده
منابع مشابه
Of genes and genomes.
Nancy Wexler’s presentation gives a clear impression of what motivates researchers to find out what genes do, especially in humans. I’ll give you the nuts and bolts of how we learn about genes, how we get and interpret information about our genes, and how the requisite technology led to the Human Genome Project. My view (and I think, now, the general view) is that the Project was the only possi...
متن کاملGenes, Genomes and Genomics
Invited Review: Reproducible and target-specific polymerase chain reaction (PCR) amplification relies on several interrelated factors of which primer design is central. Here, we describe new free bioinformatics software, the FastPCR which was developed, and continues to be updated, based on detailed experimental studies of PCR efficiency for the optimal design of primers and probe sequences and...
متن کاملMycobacteriophages: genes and genomes.
Viruses are powerful tools for investigating and manipulating their hosts, but the enormous size and amazing genetic diversity of the bacteriophage population have emerged as something of a surprise. In light of the evident importance of mycobacteria to human health--especially Mycobacterium tuberculosis, which causes tuberculosis--and the difficulties that have plagued their genetic manipulati...
متن کاملComprehensive characterization of cancer genes in hepatocellular carcinoma genomes
The present study was performed to detect moderate or low-frequency mutated cancer driver genes in hepatocellular carcinoma (HCC), using OncodriveFM and Dendrix. Following this, integrated analyses were conducted on these novel cancer driver genes. A total of 112,980 somatic mutations were retrieved from TCGA and classified into 11 categories based on their function. Driver genes and pathways w...
متن کاملSomatic Mutations in Breast Cancer Genomes: Discovery and Validation of Breast Cancer Genes
Jiao, X. 2012. Somatic Mutations in Breast Cancer Genomes: Discovery and Validation of Breast Cancer Genes. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 822. 53 pp. Uppsala. ISBN 978-91-554-8490-3. Breast cancer is the most common cancer in women worldwide. However, the genetic alterations that lead to breast cancer are no...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2005
ISSN: 1465-542X
DOI: 10.1186/bcr1082